The passion to find answers is inspiring. I had the good fortune to attend the KCNQ2 Cure Summit 2018. Meeting the patient families and seeing their passion to find answers, brings meaning and urgency to the work I have been doing to develop high-throughput drug screening platforms. What can we do to help these families? […]
C. elegans in the News
The philosopher Friedrich Nietzsche once said: “You have evolved from worm to man, but much within you is still worm.” Genetic diversity in individuals and between species is responsible for bewildering variability and biological niche adaptation of life, yet much of the essential genes involved in disease presentation are highly conserved from yeast to humans. […]
‘Those of us who have studied invertebrate model organisms throughout our careers have been nervous that NIH study sections will shut the door on our funding in favor of funding studies in mammals. But my last grant application to the NIH proposing experiments in C. elegans got a perfect score! ‘
Dr. Andy Golden at NIH discusses his work on identifying regulators and interactors of conserved genes in C. elegans that, when mutated, can cause human disease and opportunities to use C. elegans as a model in clinical and translational research.
Scientists from Duke University captured the cellular break-ins in C. elegans, a transparent worm that’s often used as a model for human biology. The cellular invasions are a normal part of the body’s development — but in cancer cells, the process goes haywire and leads to metastasis.