Automated Quantitative Phenotyping using C. elegans
C. elegans has phenotypes that can be directly related to human disease genes, with homologs identified for up to 80% of human disease genes.
Furthermore, the cellular and molecular details of the phenotypes of many human diseases and the mutant defects in C. elegans are highly related, making it a powerful experimental model organism for investigating human diseases and allowing researchers to explore and discover new phenotypes that are difficult and expensive to assess using traditional models and methods.
Visualize C. elgans feeding in real time
ScreenChip System by NemaMetrix
The ScreenChip System is an automatic screening and phenotyping platform. This platform allows researchers to rapidly generate and collect precise whole-animal data. It is a quick and reliable way to assess neuronal and physiological responses to genetic mutations, drug effects and other environmental changes.
The platform provides an alternative to enable researchers to better understand human diseases and explore potential treatments for high-impact disorders.
Discover New Phenotypes from “Nature’s Gift to Science”
Nobel prize laureate Sydney Brenner once said that C. elegans is ‘nature’s gift to science’ due to its transparent body, short lifespan, easy genetic manipulation, exquisitely defined nervous system, and most importantly, well-understood genetics. C. elegans was the first multicellular organism to have its whole genome sequenced.
See how our customers use the ScreenChip System to explore new phenotypes and advance their research.