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Fig 1. Day-2 ALZ PSEN1 Knock-out live worm on NGM plate. This worm was dyed with both RediStain™ WormDyes Lyso (magenta) and Neuro Green (cyan) to stain sensory neurons and apoptotic corpses in the gonad respectively. The sel-12(ty11) mutation produces defects in vulva and neuronal development leading to a dysfunctional uterine-vulval connection and ultimately the inability to lay eggs. The worm is positioned head-down on the left and head-up on the right.