Our Co-founder, Dr. Weeks, gave an impassioned scientific talk in Gabon, discussing her work at the University of Oregon that led her to start NemaMetrix and receive a Bill & Melinda Gates Foundation grant for global health research.
There is a critical need for new anthelmintic drugs for humans and animals, largely because of increasing resistance of the parasites to existing drugs. The new technology was invented by Dr. Shawn Lockery, UO professor of biology and the other co-founder of NemaMetrix.
Many of the most effective anthelmintic drugs target proteins involved in electrical signaling in worms yet, previously, there was no efficient method to test for this property during the drug discovery process. The microfluidic chips provide a medium-throughput, semi-automated and non-invasive method for recording the electrical activity of neurons and muscles in nematodes while applying test compounds.