Accelerate Your Science With Humanized or Customized Transgenics
Many human diseases are caused by mutations in the genome. Recent progress in DNA sequencing has identified massive amounts of rare alleles that appear to be clinically associated with a disease. Yet, definitive proof of pathogenicity remains unknown for many of the uncovered clinical variants.
Using humanized C. elegans as a model system, Knudra has the expertise to provide the transgenics you need through:
- RediMODEL Kits – three types of C. elegans animal models engineered for human disease discovery.
RediSERVICE – customized genome engineering services to fit a variety of project types using the latest CRISPR/Cas9 genome editing techniques
See how we explore new phenotypes using humanized worms
- Blog: Searching for a cure for Niemann-Pick Type C using C. elegans
- Poster: A humanized test system: Using pharyngeal pumping phenotypes as a readout for the serotonergic signaling pathway in C. elegans (presented at 2017 Int’l Worm Meeting