I assessed the risk of contamination of the freeze dried bacteria on a plate and made preliminary observations about N2 development on this food source. It seems that when cultivated on freeze dried bacteria lawns, worms seem to avoid the lawns and show developmental delay or at least a larger size discrepancy between individuals that under normal conditions.
Aging & Healthspan
I started my experiments based on the plan. I tried different levels of concentration. The initial results were mixed.
I have had my eyes on LabTie’s freeze dried bacteria for a couple of months now. It could be a great way to reduce the variability of food source and streamline worm maintenance without having to deal with overnight incubation. I decided to put this food source to the test before potentially making it part of my worms’ diet.
If this food source turns out to be of good quality, it would definitely be a game changer in our lab.
Interesting data using C. elegans for studying the impact your gut microbiome may have on your lifespan and healthspan from the Wang Lab at Baylor College of Medicine. The study highlights the power of C. elegans as a tool for whole animal discovery – the work would have been impossible to carry out using cultured cells and would have been prohibitively expensive in mice.
C. elegans’ feeding behavior strongly influences the worm’s aging and longevity. We tested adult worms to quantify how aging affects their feeding behavior. In older adults, pharyngeal pumping was weaker and less regular.