Effects of serotonin in mammals can be modeled using pharyngeal pumping phenotypes in C. elegans Terra Hiebert, Ph. D. Serotonin is well known for being important in the regulation of people’s mood. Here in the Pacific Northwest, our long overcast winters have made many of us very familiar with the mood improving effects of [...]
Microfluidic electropharyngeograms confirm and extend the phenotypic analysis of glutamate neurotransmission mutants in C. elegans
Shawn Lockery, Ph.D. | This technical note demonstrates that the ScreenChip System can reproduce the expected effects of pumping mutants in which glutamate transmission is disrupted. It also illustrates new mechanistic insights the system can provide.